Vascular Biology

Cardiovascular diseases (CVD) cause more deaths per year than the next six leading causes of death combined. There is also strong evidence for a role of oxidative stress, a key focus at Oxford Biomedical Research, in the development of CVD. Emerging risk factors for CVD include isoprostanes, C-reactive proteins, fibrinogen and plasminogen activator inhibitor 1 (PAI-1). Fibrinogen and PAI-1 are key components of the highly regulated coagulation process. Elevated PAI-1 transcription has been reported to be caused by oxidative stress activation of the AP-1 response element. Vascular endothelial cells also play a key role in cancer by limiting the access of circulating cells to sub-endothelial space and thereby reducing tumor metastasis.

We offer a wide range of antibodies, purified and recombinant proteins, and immunoassay kits for studies of proteins involved in cardiovascular biology – including those that play key roles in coagulation and its regulation, as well as other proteins that have been recognized as important in cardiovascular pathobiology.

Displaying 1-30 of 503 products
PRODUCT CATALOG # SIZE PRICEsort icon
Human fibrinogen, plasminogen depleted CT13 25 mg $110.00
FITC Labeled Human Fibrinogen CT53 10 mg $110.00
Dog Fibrinogen CT29 1.0 mg $130.00
Inhibitory monoclonal antibody to human prorenin, clone 4B5-E3 RN39 0.1 mg $145.00
Monoclonal antibody to human prorenin, clone 6E2-B7 RN42 0.1 mg $145.00
Monoclonal antibody to human renin and prorenin, clone 7D3-E3 RN43 0.1 mg $145.00
Bovine Fibrinogen CT28 25 mg $165.00
FITC Labeled Bovine Fibrinogen CT51 10 mg $165.00
FITC Labeled Sheep Fibrinogen FB09 10 mg $175.00
Human Antithrombin CT01 1.0 mg $180.00
Human Fibronectin GP40 1.0 mg $180.00
Human Glu Plasminogen PL20 1.0 mg $180.00
Bovine Plasminogen PL24 1.0 mg $180.00
Sheep Fibrinogen FB08 100 mg $200.00
Sheep Anti Human Plasminogen Antiserum PL69 1.0 ml $200.00
Porcine Pancreatic Elastase SP23 10 mg $200.00
Sheep anti-Human Factor XIII CF52 1.0 mg $210.00
Sheep anti-Human Prothrombin CT41 1.0 mg $210.00
Sheep anti-Human Prothrombin - Affinity Purified CT42 0.1 mg $210.00
Sheep Anti Human plasminogen IgG PL70 1.0 mg $210.00
Human alpha-thrombin CT36 1.0 mg $215.00
Sheep Anti Human Factor IX antiserum CF02 1.0 ml $220.00
Sheep Anti Human Factor IX IgG fraction CF03 1.0 mg $220.00
Sheep anti human factor XII antiserum CF47 1.0 ml $220.00
Sheep anti human factor XII IgG fraction CF48 1.0 mg $220.00
Sheep Anti Human tPA antiserum PA36 1.0 ml $220.00
Sheep Anti Human tPA IgG fraction PA37 1.0 mg $220.00
Sheep Anti Mouse & Rat tPA antiserum PA38 1.0 ml $220.00
Sheep Anti Mouse & Rat tPA IgG fraction PA39 1.0 mg $220.00
Human tPA (>85% single chain) PA51 0.1 mg $220.00
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