Vascular Biology

Cardiovascular diseases (CVD) cause more deaths per year than the next six leading causes of death combined. There is also strong evidence for a role of oxidative stress, a key focus at Oxford Biomedical Research, in the development of CVD. Emerging risk factors for CVD include isoprostanes, C-reactive proteins, fibrinogen and plasminogen activator inhibitor 1 (PAI-1). Fibrinogen and PAI-1 are key components of the highly regulated coagulation process. Elevated PAI-1 transcription has been reported to be caused by oxidative stress activation of the AP-1 response element. Vascular endothelial cells also play a key role in cancer by limiting the access of circulating cells to sub-endothelial space and thereby reducing tumor metastasis.

We offer a wide range of antibodies, purified and recombinant proteins, and immunoassay kits for studies of proteins involved in cardiovascular biology – including those that play key roles in coagulation and its regulation, as well as other proteins that have been recognized as important in cardiovascular pathobiology.

Displaying 331-360 of 503 products
PRODUCT CATALOG # SIZE PRICEsort icon
Anti-Mouse tPA Affinity Purified (high titer) PT34 0.1 mg $345.00
Anhydrotrypsin SP30 0.1 mg $345.00
Porcine Pancreatic Elastase SP31 1.0 ml $345.00
Human PAI-1 tPA Complex UP44 0.1 mg $345.00
Recombinant Human LMW urokinase, Insect Cell VA70 0.1 mg $345.00
Human Factor IXa, Active Site Labeled with Fluorescein CF12 0.1 mg $335.00
Sheep Anti Mouse Factor X antiserum CF04 1.0 ml $330.00
Sheep Anti Mouse Factor X IgG fraction CF05 1.0 mg $330.00
Affinity Purified Sheep Anti Mouse Factor X CF08 0.1 mg $330.00
Rabbit anti human factor X antiserum CF29 1.0 ml $330.00
Rabbit anti human factor X IgG fraction CF30 1.0 mg $330.00
Sheep anti-Murine Factor X (Immuno absorbed) CF45 0.1 mg $330.00
Sheep anti mouse Protease Nexin 1 antiserum NX02 1.0 ml $330.00
Sheep anti mouse Protease Nexin 1 IgG fraction NX03 1.0 mg $330.00
Non-enzymatic Human tPA PA44 0.1 mg $330.00
Non-enzymatic, non-cleavable Human tPA PA46 0.1 mg $330.00
Human tPA, Non-cleavable PA49 0.1 mg $330.00
Non-enzymatic, non-cleavable Mouse tPA PA50 0.1 mg $330.00
Human tPA (>95% two chain) PA54 0.1 mg $330.00
Active Mouse tPA (recombinant) PA56 0.1 mg $330.00
Biotin labeled Mouse tPA PA72 0.05 mg $330.00
FITC labeled Mouse tPA PA73 0.05 mg $330.00
Mouse tPA, Non-cleavable PA74 0.1 mg $330.00
Non-enzymatic Mouse tPA PA76 0.1 mg $330.00
Active Rabbit tPA (recombinant ) PA77 0.1 mg $330.00
Active Rat tPA (recombinant ) PA78 0.1 mg $330.00
Sheep Anti Mouse Neuroserpin Antiserum PR51 1.0 ml $330.00
Sheep Anti Mouse Neuroserpin IgG Fraction PR52 1.0 mg $330.00
Rabbit anti human prorenin antiserum RN25 1.0 ml $330.00
Rabbit anti human prorenin IgG fraction RN26 1.0 mg $330.00
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